Chips only need microliter size samples can detect lung cancer cells for high accuracy.
In order to shorten the time and increase the efficiency of diagnosing lung cancer cells, a microfluidic chip is made by a research team at Vietnam University of Technology after 4 years of research. The chip requires only a few blood samples and the reagents can detect lung cancer cells with a short processing time.
In current screening techniques, doctors usually take the patient’s blood, use specific antibodies to look for the presence of cyclic cancer cells (a rare population of cancer cells, which are captured. source from primary tumor or metastatic tumor). However, this method only works if cancer cells appear in large numbers, difficult to find if in small numbers.
“Developing a rapid detection device for recirculating cancer cells is an important task to treat cancers in the country. This device must have a full range of functions from screening, cell enrichment to trapping and capture target cells, perform cell concentration measurements, convert to electronic information for processing in the controller “.- Head of the study team, said.
The chip is designed and developed by the team based on microfluidic technology, transferred from Taiwan. The device has a system of microfluidic channels with a size of several tens of micrometres, allowing multiple processes to be integrated on one platform, reducing sample time and volume. Therefore, cells in channels need only a smaller volume than microliter, but the cell concentrations during the experiment can still be kept high without dilution. Detecting and meeting sensitivity and precision requirements is made easier.